Unlocking tumor vascular barriers with CXCR3: Implications for cancer immunotherapy.
Unlocking tumor vascular barriers with CXCR3: Implications for cancer immunotherapy.
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DOI：
10.1080/2162402x.2015.1116675
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发表时间：
2016-05
期刊：
影响因子：
7.2
通讯作者：
Evans SS
中科院分区：
文献类型：
--
作者：
Mikucki ME;Skitzki JJ;Frelinger JG;Odunsi K;Gajewski TF;Luster AD;Evans SS
Promising cancer immunotherapeutics depend on mobilization of cytotoxic T cells across tumor vascular barriers through mechanisms that are poorly understood. Recently, we discovered that the CXCR3 chemokine receptor uniquely functions as the master-regulator of cytotoxic CD8+ T cell extravasation and tumor control despite the multiplicity of chemokines available in the tumor landscape.
