Ovarian follicle count by magnetic resonance imaging is greater in adolescents and young adults with polycystic ovary syndrome than in controls.
Ovarian follicle count by magnetic resonance imaging is greater in adolescents and young adults with polycystic ovary syndrome than in controls.
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DOI：
10.1016/j.xfre.2022.01.008
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发表时间：
2022-06
期刊：
影响因子：
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通讯作者：
Sopher, Aviva B
中科院分区：
文献类型：
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作者：
Pereira-Eshraghi, Camila Freitas;Tao, Rachel;Chiuzan, Codruta C;Zhang, Yuan;Shen, Wei;Lerner, Jodi P;Oberfield, Sharon E;Sopher, Aviva B
目的：应用磁共振成像（MRI）双平面测量法定量每个卵巢的卵泡数（FNPO），三维测量法测定多囊卵巢综合征（PCOS）青少年和青年患者与对照组的卵巢体积（OV），比较两组间的差异，探讨FNPO和OV与PCOS相关代谢指标的关系;比较年轻PCOS患者和对照组通过MRI和超声获得的OV。横断面研究。纽约市一家大型医疗中心的门诊病人。年龄在13-25岁的青春期女孩和年轻女性PCOS患者（n = 16）和体重指数、年龄和种族相当的对照受试者（n = 15）。一个也没有。通过使用MRI进行OV和FNPO，通过使用经腹盆腔超声进行OV，人体测量以及生化和激素评估。当调整月经年龄时，PCOS参与者的FNPO（23.7 ± 4.6个卵泡）高于对照组（15.2 ± 4个卵泡）。PCOS受试者使用超声检查的OV（11.7 ± 5.6 mL）高于对照组（8.1 ± 3.4 mL）;然而，使用MRI检查的OV在两组之间没有差异。使用MRI和超声检查的OV与PCOS患者相关（r = 0.62），但与对照组无关。我们的结果与先前的研究一致，表明FNPO可能是比OV更敏感的多囊卵巢形态学指标。这项研究的结果支持在年轻患者中使用卵巢K，这是一种有前途的PCOS诊断工具。
To use magnetic resonance imaging (MRI) to quantify the follicle number per ovary (FNPO) using biplanar measurements and determine the ovarian volume (OV) using three-dimensional measurements in adolescents and young adults with polycystic ovary syndrome (PCOS) and controls and compare the differences between these groups; to examine the relationships between FNPO and OV and metabolic markers associated with PCOS; to compare OV obtained by use of MRI and ultrasound between young patients with PCOS and controls. Cross-sectional study. Outpatient within a major medical center in New York City. Adolescent girls and young women aged 13–25 years with PCOS (n = 16) and body mass index–, age-, and ethnicity-comparable control subjects (n = 15). None. The OV and FNPO by use of MRI, OV by use of transabdominal pelvic ultrasound, anthropometric measurements, and biochemical and hormonal evaluation. The FNPO was higher in participants with PCOS (23.7 ± 4.6 follicles) than in controls (15.2 ± 4 follicles) when adjusted for menstrual age. The OV by use of ultrasound was higher in participants with PCOS (11.7 ± 5.6 mL) than in controls (8.1 ± 3.4 mL); however, OV by use of MRI did not differ between the groups. The OV by use of MRI and ultrasound correlated in participants with PCOS (r = 0.62) but not in controls. Our results are in line with prior studies showing that FNPO may be a more sensitive measure of polycystic ovary morphology than OV. The results of this study support the use of ovarian k, a promising diagnostic tool for PCOS, in young patients.