Post-traumatic stress disorder and depression - An analysis of comorbidity
Post-traumatic stress disorder and depression - An analysis of comorbidity
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DOI：
10.1192/bjp.170.5.479
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发表时间：
1997-05-01
影响因子：
10.5
通讯作者：
Lerer, B
中科院分区：
文献类型：
--
作者：
Bleich, A;Koslowsky, M;Lerer, B
背景：我们调查了战争相关精神创伤后的精神疾病发病率，重点关注创伤后应激障碍(PTSD)的抑郁共病。方法研究对象包括60名以色列退伍军人，他们在遭受战争创伤4-6年后寻求精神治疗。采用创伤后应激障碍结构化访谈和情感障碍与精神分裂症量表对创伤后应激障碍和精神疾病共病进行诊断。结果终生创伤后应激障碍(100%)和当前创伤后应激障碍(87%)是最常见的疾病。共病的范围很广，其中重度抑郁障碍(MDD)最常见(95%终生，50%目前)，其次是焦虑症、轻微情感障碍和酒精中毒或药物滥用。结论创伤后精神疾病中，创伤后应激障碍和MDD是最常见的疾病。此外，似乎创伤后应激障碍虽然与创伤后MDD有关，但不仅仅是共同的共同症状，同时作为一个独立的诊断类别与之区分开来。
Background We examined psychiatric morbidity following war-related psychic trauma, with a special focus on the depressive comorbidity of post-traumatic stress disorder (PTSD).Method Subjects consisted of 60 Israeli veterans who sought psychiatric treatment 4-6 years after having been exposed to war trauma. PTSD and psychiatric comorbidity were diagnosed using the Structured Interview for PTSD and the Schedule for Affective Disorders and Schizophrenia.Results Both lifetime (100%) and current (87%) PTSD were the most prevalent disorders. Comorbidity was extensive, with major depressive disorder (MDD) most prevalent (95% lifetime, 50% current), followed by anxiety disorders, minor affective disorders, and alcoholism or drug misuse.Conclusions Within post-traumatic psychiatric morbidity of combat origin, PTSD and MDD are the most prevalent disorders. In addition it appears that PTSD, although related to post-traumatic MDD beyond a mere sharing of common symptoms, is at the same time differentiated from it as an independent diagnostic category.