[Comparison of clinical methods for the demonstration of radiation-induced lung changes. Experimental study on animals].

[Comparison of clinical methods for the demonstration of radiation-induced lung changes. Experimental study on animals].
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[演示辐射引起的肺部变化的临床方法比较。

DOI:
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发表时间:
1983
期刊:
RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin
影响因子:
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通讯作者:
W. Hofmann
W. Hofmann
中科院分区:
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文献类型:
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作者:
K. Schnabel;R. Siegl;U. Abel;W. Hofmann

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本研究的目的是比较不同影像学方法(X线摄影、计算机断层摄影和肺动脉造影)对肺纤维化或放射性肺炎的诊断价值。用3200 ~ 6200 rd照射50只家兔右肺。在13周的时间内通过上述方法观察肺变化。组织学检查作为评价成像方法的基础。比较表明,当密度测量包括在诊断标准中时,计算机断层扫描的优越性。准确率约为95%。闪烁照相术作为定量方法不如计算机断层扫描,使用单位面积计数的差异。放射学作为一种主观方法,其准确性约为84%,与放射照相术大致相同。
The purpose of this study was to compare the value of different imaging methods (radiography, computer tomography and scintigraphy) for demonstrating pulmonary fibrosis or radiation pneumonitis. The right lungs of 50 rabbits were irradiated with 3200 to 6200 rd. The lung changes were observed by the above methods over a period of 13 weeks. Histological examination served as the basis for evaluating the imaging methods. The comparison demonstrated the superiority of computer tomography when density measurements were included in the diagnostic criteria. The accuracy was about 95%. Scintigraphy was inferior to computer tomography as a quantitative method, using differences in the counts per unit area. Radiology as a subjective method achieved an accuracy of about 84%, approximately the same as scintigraphy.