Scleroderma-like changes in chronic graft vs host disease.
Scleroderma-like changes in chronic graft vs host disease.
复制标题
慢性移植物抗宿主病的硬皮病样变化。
DOI：
10.1001/archderm.1977.01640100102020
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发表时间：
1977
影响因子：
--
通讯作者：
J. Kersey
中科院分区：
文献类型：
--
作者：
R. Spielvogel;R. Goltz;J. Kersey
一例慢性移植物抗宿主病患者出现硬皮病样皮肤变化。临床进展是从异皮病到硬皮病，并记录了组织病理学变化和直接免疫荧光结果。细胞介导的（T 细胞）和体液（B 细胞）机制可能都有助于移植物抗宿主反应的发病机制。
A case of chronic graft vs host disease had scleroderma-like skin changes. Clinical progression was from poikiloderma to scleroderma, and histopathological changes and results of direct immunofluorescence were noted. It is probable that both cell-mediated (T-cell) and humoral (B-cell) mechanisms contribute to the pathogenesis of the graft vs host reaction.