Omega-3 and Omega-6 Intake Modifies Asthma Severity and Response to Indoor Air Pollution in Children
Omega-3 and Omega-6 Intake Modifies Asthma Severity and Response to Indoor Air Pollution in Children
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DOI：
10.1164/rccm.201808-1474oc
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发表时间：
2019-06-15
影响因子：
24.7
通讯作者：
Hansel, Nadia N.
中科院分区：
文献类型：
--
作者：
Brigham, Emily P.;Woo, Han;Hansel, Nadia N.
原理：室内颗粒物（PM）浓度较高与哮喘发病率增加有关。膳食摄入的脂肪酸，也与哮喘outcomes，可能会影响这种relationship.Objectives：为了确定ω-3和ω-6脂肪酸摄入量和儿童哮喘发病率之间的关系，以及脂肪酸摄入量和强度之间的关联室内，PM相关的哮喘症状，沙丁胺醇的使用，全身inflammation.Methods：分析包括135名儿童哮喘纳入AsthmaDIET研究。在基线、3个月和6个月时，数据包括：
Rationale: Higher indoor particulate matter (PM) concentrations are linked with increased asthma morbidity. Dietary intake of fatty acids, also linked with asthma outcomes, may influence this relationship.Objectives: To determine the relationship between omega-3 and omega-6 fatty acid intake and pediatric asthma morbidity, and the association between fatty acid intake and strength of indoor, PM-related asthma symptoms, albuterol use, and systemic inflammation.Methods: Analyses included 135 children with asthma enrolled in the AsthmaDIET Study. At baseline, 3 months, and 6 months, data included: week-long average home indoor concentration of PM