Spirituality and autonomic cardiac control
Spirituality and autonomic cardiac control
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DOI：
10.1007/s12160-008-9027-x
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发表时间：
2008-04-01
影响因子：
3.8
通讯作者：
Cacioppo, John T.
中科院分区：
文献类型：
--
作者：
Berntson, Gary G.;Norman, Greg J.;Cacioppo, John T.
背景 灵性被认为与积极的健康有关，但潜在的生物介质尚未得到很好的表征。 目的和方法本研究在以中老年人为基础的人群样本中检验了灵性与心脏自主控制模式之间的潜在关系，这可能具有健康意义。从 229 名参与者的代表性样本中获得了副交感神经（高频心率变异性）和交感神经（射血前期）心脏控制的测量结果。参与者完成了问卷调查以评估灵性（与上帝的亲密程度和令人满意的关系）。还获得了个性、人口统计、人体测量、健康行为和健康状况信息。使用一系列分层回归模型来检查灵性、自主神经测量和两个派生指标——心脏自主平衡（CAB，反映副交感神经到交感神经平衡）和心脏自主调节（CAR，反映完全自主控制）之间的关系。结果发现，灵性、人口统计学或其他变量与增强的副交感神经和交感心脏控制有关 （产生更高的 CAR）但与 CAB 无关。尽管病例数很少（N = 11），但灵性和 CAR 都是先前发生心肌梗死的显着负预测因子。 结论 在基于人群的样本中，灵性似乎与 CAR 的特定模式相关，其特征是高水平的心脏自主控制，无论两个自主神经分支的相对贡献如何。这种自主控制模式可能具有健康意义。
Background Spirituality has been suggested to be associated with positive health, but potential biological mediators have not been well characterized.Purpose and Methods The present study examined, in a population-based sample of middle-aged and older adults, the potential relationship between spirituality and patterns of cardiac autonomic control, which may have health significance. Measures of parasympathetic (high-frequency heart rate variability) and sympathetic (pre-ejection period) cardiac control were obtained from a representative sample of 229 participants. Participants completed questionnaires to assess spirituality (closeness to and satisfactory relationship with God). Personality, demographic, anthropometric, health behavior, and health status information was also obtained. A series of hierarchical regression models was used to examine the relations between spirituality, the autonomic measures, and two derived indexes-cardiac autonomic balance (CAB, reflecting parasympathetic to sympathetic balance) and cardiac autonomic regulation (CAR, reflecting total autonomic control).Results Spirituality, net of demographics, or other variables were found to be associated with enhanced parasympathetic as well as sympathetic cardiac control (yielding a higher CAR) but was not associated with CAB. Although the number of cases was small (N=11), both spirituality and CAR were significant negative predictors of the prior occurrence of a myocardial infarction.Conclusions In a population-based sample, spirituality appears to be associated with a specific pattern of CAR, characterized by a high level of cardiac autonomic control, irrespective of the relative contribution of the two autonomic branches. This pattern of autonomic control may have health significance.