Peroxisome proliferator‐activated receptor γ ligand troglitazone induces cell cycle arrest and apoptosis of hepatocellular carcinoma cell lines

Peroxisome proliferator‐activated receptor γ ligand troglitazone induces cell cycle arrest and apoptosis of hepatocellular carcinoma cell lines
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过氧化物酶体增殖物激活受体γ配体曲格列酮诱导肝癌细胞系细胞周期阻滞和凋亡

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发表时间:
2002
期刊:
影响因子:
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通讯作者:
K. Kiyosawa
K. Kiyosawa
中科院分区:
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文献类型:
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作者:
K. Yoshizawa;D. Cioca;S. Kawa;E. Tanaka;K. Kiyosawa

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过氧化物酶体增殖物激活受体γ(过氧化物酶体增殖物激活受体γ)的配体激活导致各种癌细胞增殖的抑制。本研究旨在探讨过氧化物酶体增殖物激活受体γ(PPARγ)配体曲格列酮(troglitazone)对肝癌细胞生长抑制的机制。
Ligand activation of peroxisome proliferator‐activated receptor γ (PPARγ) results in the inhibition of proliferation of various cancer cells. The aim of this study is to investigate the mechanisms of cell growth inhibition of hepatocellular carcinoma (HCC) cell lines by the PPARγ ligand, troglitazone.
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发表时间: 1996-11
影响因子: 4.4
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