Rhodium catalysed enantioselective hydroboration of alkenylboronic esters with catecholborane
Rhodium catalysed enantioselective hydroboration of alkenylboronic esters with catecholborane
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DOI：
10.1016/0957-4166(95)00407-6
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发表时间：
1996-01-01
影响因子：
--
通讯作者：
Weissensteiner, W
中科院分区：
文献类型：
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作者：
Wiesauer, C;Weissensteiner, W
以邻苯二酚硼烷为催化剂，用各种双膦配体修饰的中性和阳离子铑配合物，对烯基硼酸酯如（E）-2-（2-苯乙烯基）-1，3，2-二氧硼杂环戊烷进行了催化硼氢化反应。所得1，2-二硼基中间体用碱性过氧化氢氧化，得到相应的1，2-二醇，对映选择性高达79%e. e.
Alkenylboronic esters such as (E)-2-(2-phenylethenyl)-1,3,2-dioxaborolane were subjected to catalytic hydroboration with catecholborane and with use of neutral and cationic rhodium complexes modified by various diphosphine ligands. The resulting 1,2-diboryl intermediate was oxidised with alkaline hydrogen peroxide to give the corresponding 1,2-diol with enantioselectivities up to 79 % e.e.