Lifetime prevalence and age-of-onset distributions' of DSM-IV disorders in the national comorbidity survey replication
Lifetime prevalence and age-of-onset distributions' of DSM-IV disorders in the national comorbidity survey replication
复制标题
DOI：
10.1001/archpsyc.62.6.593
复制
发表时间：
2005-06-01
影响因子：
--
通讯作者：
Walters, EE
中科院分区：
文献类型：
--
作者：
Kessler, RC;Berglund, P;Walters, EE
内容：DSM-IV疾病的终生患病率或发病年龄知之甚少。目的：在最近完成的全国科摩罗重复调查中估计DSM-IV疾病的终生患病率和发病年龄分布。设计和设置：国家代表面对面2001年2月至2003年4月期间进行的面对面家庭调查，使用的是世界卫生组织结构完整的世界精神卫生调查版本，研究对象为9282名年龄在18岁以上的讲英语的受访者，主要结果测量：终生DSM-IV焦虑、情绪、冲动控制和物质使用障碍。物质使用障碍，14.6%;任何障碍，46.4%。焦虑（11岁）和冲动控制（11岁）障碍的发病年龄中位数比物质使用（20岁）和情绪（30岁）障碍早得多。所有终生病例中有一半始于14岁，四分之三始于24岁。晚期发病大多是共病，75岁时任何疾病的估计终生风险（50.8%）仅略高于观察到的终生患病率（46.4%）。终生患病率估计是较高的，在最近的队列比在早期的队列，并有相当稳定的跨队列的差异，在整个生命过程中的变化，在实质上合理的方式sociodemographic subgroup.Conclusions：约有一半的美国人将符合标准的DSM-IV障碍的某个时候在他们的生活中，首次发病通常在儿童或青春期。旨在预防或早期治疗的干预措施需要以青年为重点。
Context: Little is known about lifetime prevalence or age of onset of DSM-IV disorders.Objective: To estimate lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the recently completed National Comorbidity Survey Replication.Design and Setting: Nationally representative face-to-face household survey conducted between February 2001 and April 2003 using the fully structured World Health Organization World Mental Health Survey version of the Composite International Diagnostic Interview.Participants: Nine thousand two hundred eighty-two English-speaking respondents aged 18 years and older.Main Outcome Measures: Lifetime DSM-IV anxiety, mood, impulse-control, and substance use disorders.Results: Lifetime prevalence estimates are as follows: anxiety disorders, 28.8%; mood disorders, 20.8%; impulse-control disorders, 24.8%; substance use disorders, 14.6%; any disorder, 46.4%. Median age of onset is much earlier for anxiety (I I years) and impulse-control (11 years) disorders than for substance use (20 years) and mood (30 years) disorders. Half of all lifetime cases start by age 14 years and three fourths by age 24 years. Later onsets are mostly of comorbid conditions, with estimated lifetime risk of any disorder at age 75 years (50.8%) only slightly higher than observed lifetime prevalence (46.4%). Lifetime prevalence estimates are higher in recent cohorts than in earlier cohorts and have fairly stable intercohort differences across the life course that vary in substantively plausible ways among sociodemographic subgroups.Conclusions: About half of Americans will meet the criteria for a DSM-IV disorder sometime in their life, with first onset usually in childhood or adolescence. Interventions aimed at prevention or early treatment need to focus on youth.