Translation of laser-based three-dimensional printing technologies
Translation of laser-based three-dimensional printing technologies
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DOI：
10.1557/s43577-021-00042-2
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发表时间：
2021-02-12
期刊：
影响因子：
5
通讯作者：
Narayan, Roger J.
中科院分区：
文献类型：
--
作者：
Baldacchini, Tommaso;Saksena, Jayant;Narayan, Roger J.
基于激光的三维（3D）打印方法，包括激光直写细胞打印和双光子聚合，由于其独特的光子特性而取得了重大进展。已经开发了几种机制来提高双光子聚合的总体吞吐量。最近还展示了使用激光直写细胞打印开发复杂医学相关结构的努力；例如，微血管网络血管生成过程中癌细胞动态的延时成像离体实验平台，该平台将激光直写细胞打印技术结合到大鼠肠系膜培养模型中；模拟三维体内培养的模型。激光3D打印方法对组织工程支架、微结构医疗设备和其他医学相关结构的3D打印具有重要的前景。
Laser-based three-dimensional (3D) printing methods, including laser direct-write cell printing and two-photon polymerization, have seen significant advances because of their unique photonic characteristics. Several mechanisms have been developed to increase the overall throughput of two-photon polymerization. Recent efforts to develop complex medically relevant structures using laser direct-write cell printing have also been demonstrated; for example, an ex vivo experimental platform for time-lapse imaging of cancer cell dynamics during angiogenesis within a microvascular network, which combines laser direct-write cell printing into the rat mesentery culture model; a model that simulates a 3D in vivo culture. Laser 3D printing methods hold significant promise for 3D printing of tissue engineering scaffolds, microstructured medical devices, and other medically relevant structures.