Dynamics of Sleep-Wake Cyclicity Across the Fetal Period in Sheep (Ovis aries)
Dynamics of Sleep-Wake Cyclicity Across the Fetal Period in Sheep (Ovis aries)
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DOI：
10.1002/dev.20495
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发表时间：
2011-01-01
影响因子：
2.2
通讯作者：
Blumberg, M. S.
中科院分区：
文献类型：
--
作者：
Karlsson, K. A. E.;Arnardottir, H.;Blumberg, M. S.
到目前为止，所有的成年哺乳动物表现出睡眠回合持续时间，遵循指数分布和唤醒回合持续时间，遵循幂律分布。在老年啮齿动物如大鼠和小鼠中，出生后不久就发现睡眠发作的指数分布，但唤醒发作的幂律分布直到出生后第三周才出现。此外，睡眠和发作都在产后早期巩固。目前还不知道是否类似的发育过程发生在早熟物种在产前期间。在这里，我们的特点睡眠觉醒的发展，早熟的物种，国内绵羊（绵羊），从114至148天胎龄（DGA）。睡眠和觉醒发作持续时间在整个胎儿期呈指数分布，有证据表明，在妊娠结束时，觉醒发作呈指数到幂律的过渡。睡眠和清醒的发作在整个发展过程中以有序的方式巩固，几乎没有证据表明昼夜节律的变化，即使在最古老的受试者中也是如此。这些结果表明，类似的模式的睡眠-觉醒组织被发现产前在早熟的物种是发现产后在altricial物种。需要更多物种的数据，以充分认识到发展的比较方法的好处，了解的力量，塑造了哺乳动物睡眠的个体发育和发育。(C)2010 Wiley Periodicals，Inc. Dev Psychobiol 53：89-95，2011.
All adult mammals examined thus far exhibit sleep bout durations that follow an exponential distribution and wake bout durations that follow a power-law distribution. In altricial rodents such as rats and mice, exponential distributions of sleep bouts are found soon after birth, but the power-law distribution of wake bouts does not emerge until the third postnatal week. Also, both sleep and bouts consolidate across the early postnatal period. It is not known whether similar developmental processes occur in precocial species during the prenatal period. Here we characterize sleep-wake development in a precocial species, the domestic sheep (Ovis aries), from 114 to 148 days gestational age (DGA). Sleep and wake bout durations exhibited exponential distributions throughout the fetal period with some evidence of an emerging exponential-to-power- law transition for wake bouts toward the end of gestation. Both sleep and wake bouts consolidated in an orderly fashion across development and there was little evidence of circadian variation, even in the oldest subjects. These results indicate that similar patterns of sleep-wake organization are found prenatally in a precocial species as are found postnatally in altricial species. Data from more species are needed to fully realize the benefits of a developmental comparative approach for understanding the forces that have shaped the ontogeny and phylogeny of mammalian sleep. (C) 2010 Wiley Periodicals, Inc. Dev Psychobiol 53: 89-95, 2011.