Community consumption of antibacterial drugs within the Jordanian population: sources, patterns and appropriateness

Community consumption of antibacterial drugs within the Jordanian population: sources, patterns and appropriateness
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DOI:
10.1016/j.ijantimicag.2005.07.014
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发表时间:
2005-11-01
影响因子:
10.8
通讯作者:
Yousef, AM
Yousef, AM
中科院分区:
医学2区
文献类型:
--
作者:
Al-Bakri, AG;Bustanji, Y;Yousef, AM

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这项研究是同类研究中第一项评估约旦人群抗菌药物消费来源、模式和适当性的研究。它对来到社区药店寻找治疗全身感染的抗菌药物的顾客进行结构化随机访谈。根据解剖治疗化学(ATC)分类系统,配发的抗菌药物属于全身使用的抗菌药物的八个不同的主要类别。不到一半的抗菌药物没有处方(46%),无论是通过自我用药(23.2%)还是药剂师推荐(23.1%)。处方抗菌药和非处方抗菌药(非处方)的使用不当比例分别为 29.9% 和 34%。不同治疗投诉的治疗情况没有发现一致性。我们的研究显示抗菌药物的误用和滥用现象严重,因此有必要强制制定法规来控制抗菌药物的社区使用,并提高对其不当和不受控制使用后果的认识。 (C) 2005 Elsevier B.V. 和国际化疗协会。版权所有。
This study is the first of its type to evaluate sources, patterns and appropriateness of antibacterial drug consumption within the Jordanian population. It uses a structured random interview to customers arriving at community pharmacy stores seeking antibacterial medication for systemic infections. Dispensed antibacterial drugs belonged to eight different main classes of systemically used antibacterial drugs in accordance with the Anatomical Therapeutic Chemical (ATC) classification system. Just less than one-half of all dispensed antibacterial drugs were without a prescription (46%), either via self-medication (23.2%) or pharmacist recommendation (23.1%). Inappropriateness in use was seen in 29.9% and 34% of the prescribed and non-prescribed (over-the-counter) antibacterial drugs, respectively. No uniformity in the treatment profile of the different treated complaints was seen. Our study shows great misuse and abuse of antibacterial drugs and hence there is a need to force regulations to control community use of antibacterial drugs and to increase awareness of the consequences of their inappropriate and uncontrolled use. (C) 2005 Elsevier B.V. and the International Society of Chemotherapy. All rights reserved.