The evaporative light scattering detector: some applications in pharmaceutical analysis

The evaporative light scattering detector: some applications in pharmaceutical analysis
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DOI:
10.1016/s0165-9936(97)00072-1
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发表时间:
1997-09-01
影响因子:
13.1
通讯作者:
Veuthey, JL
Veuthey, JL
中科院分区:
化学1区
文献类型:
--
作者:
Kohler, M;Haerdi, W;Veuthey, JL

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蒸发光散射检测器允许直接检测所有非挥发性化合物,而不管其化学结构如何,因此它是确定无发色团化合物的有价值的工具。该检测器可与液相色谱和填充超临界流体色谱相结合。本文介绍了该方法的原理,并给出了在药物分析中的应用实例。
The evaporative light scattering detector allows direct detection of all non-volatile compounds regardless of their chemical structure, and therefore it is a valuable tool to determine compounds without chromophores. This detector can be coupled to liquid chromatography and packed supercritical fluid chromatography. In this article, the principles are described and some examples of application to pharmaceutical analysis are given.