Noise reduction in LED light source-based photoacoustic imaging using M-sequences coding

Noise reduction in LED light source-based photoacoustic imaging using M-sequences coding
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DOI:
10.1117/12.2649032
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发表时间:
2023-03
期刊:
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影响因子:
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通讯作者:
K. Fukuda;Kazuma Hashimoto;Uma Maheswari Rajagopalan;Takahiro Kono;Jun Yamada
K. Fukuda;Kazuma Hashimoto;Uma Maheswari Rajagopalan;Takahiro Kono;Jun Yamada
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文献类型:
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作者:
K. Fukuda;Kazuma Hashimoto;Uma Maheswari Rajagopalan;Takahiro Kono;Jun Yamada

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光声成像技术是一种新型的成像技术,可以对光学吸收体进行高分辨率的测量。激光通常用作光声成像的光源,但存在许多安全限制。因此,将光源替换为安全限制较少的LED的装置正引起关注。然而,LED光源具有非常低的能量,并且产生的光声信号相应地较小。因此,光声信号被掩埋在噪声中,导致低信噪比(SNR)。平均也可以提高SNR,但难以保持高帧速率。M序列信号处理可以在保持高重复频率的同时提高信噪比,其有效性已在激光光源的光声测量中得到证实。然而,LED电源在发射和电路抖动方面具有时间延迟,这会影响解码。因此,我们提出了一种新的解码算法,补偿LED抖动。然后,我们通过实验验证了在实践中使用这种信号处理的SNR改善。
Photoacoustic imaging is a new imaging technique that can measure optical absorbers with high resolution. Lasers are commonly used as light sources for photoacoustic imaging, but there are many safety restrictions. Therefore, devices in which the light source is replaced by LEDs, which have fewer safety restrictions, are attracting attention. However, LED light sources have very low energy, and the photoacoustic signal generated is correspondingly small. Therefore, the photoacoustic signal is buried in noise, resulting in a low signal-to-noise ratio (SNR). Averaging can also improve SNR, but it is difficult to maintain a high frame rate. M-sequence signal processing can improve SNR while maintaining a high repetition rate, and its effectiveness has been demonstrated in photoacoustic measurements of laser light sources. However, LED power supplies have time delays in emission and circuit jitter, which affect decoding. Therefore, we propose a new decoding algorithm that compensates for LED jitter. We then experimentally verified the SNR improvement using this signal processing in practice.