Training voluntary motor suppression with real-time feedback of motor evoked potentials.
Training voluntary motor suppression with real-time feedback of motor evoked potentials.
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通过运动诱发电位的实时反馈来训练自愿运动抑制。
DOI:
10.1152/jn.00992.2014
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发表时间:
2015
影响因子:
2.5
通讯作者:
Aron,AdamR
中科院分区:
文献类型:
--
作者:
Majid,DSAdnan;Lewis,Christina;Aron,AdamR
Training people to suppress motor representations voluntarily could improve response control. We evaluated a novel training procedure of real-time feedback of motor evoked potentials (MEPs) generated by transcranial magnetic stimulation (TMS) over motor cortex. On each trial, a cue instructed participants to use a mental strategy to suppress a particular finger representation without overt movement. A single pulse of TMS was delivered over motor cortex, and an MEP-derived measure of hand motor excitability was delivered visually to the participant within 500 ms. Inexperiment 1, we showed that participants learned to reduce the excitability of a particular finger beneath baseline (selective motor suppression) within 30 min of practice. Inexperiment 2, we performed a double-blind study with 2 training groups (1 with veridical feedback and 1 with matched sham feedback) to show that selective motor suppression depends on the veridical feedback itself.Experiment 3further demonstrated the importance of veridical feedback by showing that selective motor suppression did not arise from mere mental imagery, even when incentivized with reward. Thus participants can use real-time feedback of TMS-induced MEPs to discover an effective mental strategy for selective motor suppression. This high-temporal-resolution, trial-by-trial-feedback training method could be used to help people better control response tendencies and may serve as a potential therapy for motor disorders such as Tourette's and dystonia.
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影响因子:
3.7
作者:
C. Stinear;W. Byblow
通讯作者:
W. Byblow
影响因子:
--
作者:
Nasrin Shahana;D. Gilbert
通讯作者:
D. Gilbert
DOI:
10.1016/s1567-424x(09)70216-8
发表时间:
2003
期刊:
Supplements to Clinical neurophysiology
影响因子:
--
作者:
M. Hallett
通讯作者:
M. Hallett
影响因子:
1.6
作者:
S. A. Schapkin;M. Falkenstein;A. Marks;B. Griefahn
通讯作者:
B. Griefahn
影响因子:
3.5
作者:
Cohen, Jessica R.;Poldrack, Russell A.
通讯作者:
Poldrack, Russell A.