A glucose sensing contact lens: A non-invasive technique for continuous physiological glucose monitoring
A glucose sensing contact lens: A non-invasive technique for continuous physiological glucose monitoring
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DOI：
10.1023/a:1026103804104
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发表时间：
2003-09-01
影响因子：
2.7
通讯作者：
Geddes, CD
中科院分区：
文献类型：
--
作者：
Badugu, R;Lakowicz, JR;Geddes, CD
我们开发了一系列葡萄糖传感隐形眼镜，使用嵌入新开发的含硼酸荧光团的日抛隐形眼镜。我们的研究结果表明，我们的方法可能适合连续监测 50 1000 muM 范围内的泪液葡萄糖水平，通常跟踪血糖水平，该水平大约高出 5-10 倍。我们的非侵入性方法很可能为当前糖尿病的侵入性血糖监测技术（例如“手指刺破”）提供替代解决方案。
We have developed a range of glucose sensing contact lenses, using a daily, disposable contact lens embedded with newly developed boronic acid containing fluorophores. Our findings show that our approach may be suitable for the continuous monitoring of tear glucose levels in the range 50 1000 muM, which typically track blood glucose levels, which are approximate to5-10 fold higher. Our non-invasive approach may well offer an alternative solution to current invasive glucose monitoring techniques for diabetes, such as "finger pricking."