Noncoding RNA genes

Noncoding RNA genes
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DOI:
10.1016/s0959-437x(99)00022-2
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发表时间:
1999-12-01
影响因子:
4
通讯作者:
Eddy, SR
Eddy, SR
中科院分区:
生物学2区
文献类型:
--
作者:
Eddy, SR

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一些基因产生的RNA是功能性的,而不是编码蛋白质。非编码RNA基因数量惊人。近年来,研究热点包括核仁小RNA、反义核糖核酸调节子RNA和X剂量补偿相关RNA。基因组序列和新的算法已经开始使非编码RNA基因的系统计算筛选成为可能。
Some genes produce RNAs that are functional instead of encoding proteins. Noncoding RNA genes are surprisingly numerous. Recently, active research areas include small nucleolar RNAs, antisense riboregulator RNAs, and RNAs involved in X-dosage compensation. Genome sequences and new algorithms have begun to make systematic computational screens for noncoding RNA genes possible.