Invited commentary: low blood cholesterol, nonillness mortality, and other nonatherosclerotic disease mortality: a search for causes and confounders.
Invited commentary: low blood cholesterol, nonillness mortality, and other nonatherosclerotic disease mortality: a search for causes and confounders.
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特邀评论：低血液胆固醇、非疾病死亡率和其他非动脉粥样硬化性疾病死亡率：寻找原因和混杂因素。
DOI：
10.1093/oxfordjournals.aje.a117466
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发表时间：
1995
影响因子：
5
通讯作者：
Råstam,L
中科院分区：
文献类型：
--
作者：
JacobsJr,DR;Muldoon,MF;Råstam,L
很难解释低或降低的血液总胆固醇（TC）和各种非动脉粥样硬化疾病死亡率之间的关系。其中最令人困惑的是自杀和创伤死亡率（非疾病死亡率（NIM））的增加，在队列研究（1）和降胆固醇干预的随机试验（2）中发现与低胆固醇相关。最近有几篇关于胆固醇和NIM的综述，但文献仍然很少，结论也是试探性的（3，4）。这期杂志包含了一项横断面研究的结果，该研究检查了血脂和精神病理学之间的关系，这些关系可能与低胆固醇和NIM之间的关系有关。
It continues to be difficult to interpret observed relations between low or lowered blood total cholesterol (TC) and mortality from a variety of nonatherosclerotic conditions. Among the most perplexing is the increased suicide and traumatic death rate (nonillness mortality (NIM)) found to be associated with low cholesterol in cohort studies (1) and in randomized trials of cholesterol-lowering interventions (2). Several recent reviews on the topic of cholesterol and NIM are available, but the literature is still sparse, and the conclusions are tentative (3, 4). This issue of the Journal contains results from a cross-sectional study examining associations between serum lipids and psychopathology that are potentially relevant to the association between low cholesterol and NIM.