Phospholipid requirement for Rh antigenic activity.
Phospholipid requirement for Rh antigenic activity.
复制标题
Rh 抗原活性需要磷脂。
DOI:
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发表时间:
1968
影响因子:
4.8
通讯作者:
F. Green
中科院分区:
文献类型:
--
作者:
F. Green
Abstract The Rh antigen activity of human erythrocyte membranes was lost following extraction with 100% 1-butanol, but could be regenerated by the addition of the membrane extract or of a chloroform-methanol extract of human plasma. Studies of the extract by silicic acid and diethylaminoethyl cellulose chromatography, thin layer chromatography, and digestion with snake venom indicate that the active component is phosphatidylcholine. Preliminary data suggest that the lecithin must contain unsaturated fatty acids.