Are We Still Prescribing Opioids for Osteoarthritis?
Are We Still Prescribing Opioids for Osteoarthritis?
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DOI：
10.1016/j.arth.2017.07.030
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发表时间：
2017-12-01
影响因子：
3.5
通讯作者：
Callaghan, John J.
中科院分区：
文献类型：
--
作者：
Demik, David E.;Bedard, Nicholas A.;Callaghan, John J.
背景：美国正处于阿片类药物流行之中。这些药物继续用于治疗与骨关节炎相关的疼痛，尽管越来越多的证据质疑其益处。阿片类药物用于骨关节炎的比例在很大程度上是未知的。我们试图确定骨关节炎阿片类药物处方率，并确定与处方率较高相关的因素。2007年至2014年的行政索赔数据库。使用国际疾病分类第9版代码识别骨关节炎患者，并将其分类为髋关节、膝关节或任何关节骨关节炎。审查了索赔数据，以确定与骨关节炎诊断相关的阿片类药物处方。处方率随着时间的推移和分层的性别，年龄和地理region.Results：从2007年至2014年，17.0%的患者与任何关节骨关节炎，13.4%的髋关节骨关节炎，15.9%的膝关节骨关节炎的患者被规定为他们的条件阿片类药物。在此期间，处方的年比率相当稳定。南方的患者服用阿片类药物的几率最高，而东北部的患者最低。结论：本研究提供了关于阿片类药物用于骨关节炎的重要流行病学数据。尽管越来越多的证据对阿片类药物的益处提出质疑，并提高了对阿片类药物风险的认识，但2007年至2014年期间，处方率保持稳定。这为我们努力打击美国境内过度和不适当的阿片类药物使用提供了重要的基线数据。(C)2017爱思唯尔公司All rights reserved.
Background: The United States is in the midst of an opioid epidemic. These medications continue to be used to manage pain associated with osteoarthritis, despite mounting evidence questioning the benefits. The rate at which opioids are prescribed for osteoarthritis is largely unknown. We sought to identify rates of opioid prescriptions for osteoarthritis and identify factors associated with higher rates of prescribing.Methods: We queried the Humana, Inc. administrative claims database from 2007 to 2014. Patients with osteoarthritis were identified using International Classification of Diseases 9th Revision codes and classified as having hip, knee, or any joint osteoarthritis. Claims data were reviewed to identify opioid prescriptions associated with a diagnosis of osteoarthritis. Rates of prescribing were trended over time and stratified by sex, age, and geographic region.Results: From 2007 to 2014, 17.0% of patients with any joint osteoarthritis, 13.4% of patients with hip osteoarthritis, and 15.9% with knee osteoarthritis were prescribed an opioid for their condition. Yearly rates of prescription were fairly stable over this period. Patients in the South had the highest odds of opioid prescription, while those in the Northeast had the lowest. Patients = 50 years old.Conclusion: This study provides important epidemiologic data about the use of opioids for osteoarthritis. Despite increasing evidence calling proposed benefits into question and increasing awareness of risks of opioids, prescribing rates remained stable between 2007 and 2014. This provides important baseline data as we work to combat excessive and inappropriate opioid use within the United States. (C) 2017 Elsevier Inc. All rights reserved.