ARTERIAL STIFFNESS ASSESSMENT BY SHEAR WAVE ELASTOGRAPHY AND ULTRAFAST PULSE WAVE IMAGING: COMPARISON WITH REFERENCE TECHNIQUES IN NORMOTENSIVES AND HYPERTENSIVES
ARTERIAL STIFFNESS ASSESSMENT BY SHEAR WAVE ELASTOGRAPHY AND ULTRAFAST PULSE WAVE IMAGING: COMPARISON WITH REFERENCE TECHNIQUES IN NORMOTENSIVES AND HYPERTENSIVES
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DOI：
10.1016/j.ultrasmedbio.2018.10.032
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发表时间：
2019-03-01
影响因子：
2.9
通讯作者：
Boutouyrie, Pierre
中科院分区：
文献类型：
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作者：
Marais, Louise;Pernot, Mathieu;Boutouyrie, Pierre
对27名血压正常的参与者和29名年龄和性别匹配的原发性高血压患者进行了颈动脉脉搏波的剪切波弹性成像和超快成像，并与参考技术进行了比较：颈动脉-股动脉脉搏波速度（cfPWV）通过动脉张力测定和颈动脉僵硬度（carPWV）通过回声跟踪确定。在整个心动周期中评估颈动脉前壁（a-SWS）和后壁（p-SWS）中的剪切波速度。在收缩早期（ufPWV-FW）和收缩末期（重搏切迹，ufPWV-DN）测量超快PWV。颈动脉前壁的剪切波速度似乎是评价超快成像动脉硬度的最佳候选指标。在单变量分析中，a-SWS与carPWV（r = 0.56，p = 0.003）和颈动脉-股动脉PWV（r = 0.66，p < 0.001）相关。在多变量分析中，a-SWS与年龄（R-2 = 0.14，p = 0.02）和血压（R-2 = 0.21，p= 0.004）独立相关。此外，在整个心动周期中，a-SWS随血压增加而增加，在血压相似的情况下，血压正常的参与者和原发性高血压患者之间没有差异。(C)2018年世界医学和生物学超声联合会。All rights reserved.
Shear wave elastography and ultrafast imaging of the carotid artery pulse wave were performed in 27 normotensive participants and 29 age- and sex-matched patients with essential hypertension, and compared with reference techniques: carotid-femoral pulse wave velocity (cfPWV) determined via arterial tonometry and carotid stiffness (carPWV) determined via echotracking. Shear wave speed in the carotid anterior (a -SWS) and posterior (p-SWS) walls were assessed throughout the cardiac cycle. Ultrafast PWV was measured in early systole (ufPWV-FW) and in end-systole (dicrotic notch, ufPWV-DN). Shear wave speed in the carotid anterior appeared to be the best candidate to evaluate arterial stiffness from ultrafast imaging. In univariate analysis, a-SWS was associated with carPWV (r = 0.56, p = 0.003) and carotid-to-femoral PWV (r = 0.66, p < 0.001). In multi-variate analysis, a-SWS was independently associated with age (R-2 = 0.14, p = 0.02) and blood pressure (R-2 = 0.21, p= 0.004). Moreover, a-SWS increased with blood pressure throughout the cardiac cycle and did not differ between normotensive participants and patients with essential hypertension when compared at similar blood pressures. (C) 2018 World Federation for Ultrasound in Medicine & Biology. All rights reserved.