Multilocus sequence typing and pulsed field gel electrophoresis of otitis media causing pathogens.
Multilocus sequence typing and pulsed field gel electrophoresis of otitis media causing pathogens.
复制标题
引起中耳炎的病原体的多位点序列分型和脉冲场凝胶电泳。
DOI：
10.1007/978-1-59745-523-7_11
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发表时间：
2009
期刊：
影响因子：
--
通讯作者：
Pettigrew,MelindaM
中科院分区：
文献类型：
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作者：
Thomas,JonathanC;Pettigrew,MelindaM
肺炎链球菌、流感嗜血杆菌和卡他莫拉菌是与中耳炎相关的三种主要细菌。确定已知引起中耳炎的细菌的分子流行病学在临床和研究环境中都非常重要。PFGE和MLST为描述分离株的遗传亲缘关系提供了数据，但它们在最有用的研究类型上有所不同。因此，这两种技术的知识对于实验室打算研究中耳炎相关细菌病原体的分子流行病学是重要的。
Streptococcus pneumoniae, Haemophilus influenzae, andMoraxella catarrhalisare the three leading bacteria species associated with otitis media. Defining the molecular epidemiology of bacteria known to cause otitis media is of great importance, in both clinical and research settings. PFGE and MLST provide data for the characterization of isolates’ genetic relatedness, yet they differ in the types of studies for which they are most useful. Consequently, knowledge of both techniques is important for laboratories intending to study the molecular epidemiology of otitis media–associated bacterial pathogens.