The embryology of gut rotation.
The embryology of gut rotation.
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DOI：
10.1053/j.sempedsurg.2003.08.009
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发表时间：
2003-11-01
影响因子：
1.7
通讯作者：
Fiegel, H
中科院分区：
文献类型：
--
作者：
Kluth, D;Jaeschke-Melli, S;Fiegel, H
直到今天，令人费解的中肠“旋转不良”通常被解释为中肠旋转过程“受损”。然而，仔细研究文献发现，对这种“旋转过程”的描述是相当简略的，更多的是为了解释病理结果，而详细的适当的胚胎学研究仍然很少。尽管最近进行了一些试验，但仍然缺乏能够比较正常和异常中肠发育的良好动物模型。在本文的第一部分，“正常的旋转过程”，因为它是在文献中描述的，是提出和批判性分析。总的来说，这是一个缺点，这些关键的胚胎学过程的可靠的插图是在大多数这些论文中缺失的。因此，在本综述的第二部分，我们将介绍一系列大鼠胚胎中肠发育的扫描电镜照片。在这些图片中，没有明显的旋转过程的迹象。
Until today, the puzzling spectrum of midgut "malrotations" is commonly explained by an "impaired" process of rotation of the midgut. However, a closer look at the literature reveals that the description of this "process of rotation" is rather schematic and is aimed more at explaining pathological findings, while detailed proper embryological investigations are still rare. Despite recent trials, good animals models that would allow the comparison of normal and abnormal midgut development are still missing. In the first part of this article, the "normal process of rotation," as it is described in the literature, is presented and critically analyzed. In general, it is a shortcoming that reliable illustrations of these crucial embryological processes are missing in most of these papers. Therefore, in the second part of this review scanning electron microscopy pictures of the developing midgut are presented in a series of rat embryos. In these pictures clear signs of a process of rotation are missing.