Longitudinal and Secular Trends in Dietary Supplement Use: Nurses' Health Study and Health Professionals Follow-Up Study, 1986-2006
Longitudinal and Secular Trends in Dietary Supplement Use: Nurses' Health Study and Health Professionals Follow-Up Study, 1986-2006
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DOI：
10.1016/j.jand.2013.07.039
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发表时间：
2014-03-01
影响因子：
4.8
通讯作者：
Cho, Eunyoung
中科院分区：
文献类型：
--
作者：
Kim, Hyun Ja;Giovannucci, Edward;Cho, Eunyoung
大多数关于美国补充剂使用流行率的研究都是横断面的，或者评估了有限种类补充剂的趋势。本研究的目的是使用两个大型前瞻性队列的数据，描述过去20年卫生专业人员使用膳食补充剂的纵向和长期趋势。我们分析了1986年至2006年护士健康研究（NHS）和卫生专业人员随访研究（HPFS）的队列数据。1986年，国民保健服务中有74，194名年龄在40至65岁之间的妇女，健康和家庭保健服务中有50，497名年龄在40至75岁之间的男子。每4年重复询问一次膳食补充剂的使用情况，包括多种维生素、维生素和矿物质。重复分析采用广义估计方程模型。从1986年到2006年，妇女（71.3%）和男子（56.4%）使用任何补充剂的流行率都有所增加，从71.3%增加到88.3%，从56.4%增加到80.7%。值得注意的是，维生素D使用率的纵向增长（女性2.2%至32.2%，男性1.1%至6.7%），叶酸（妇女为0.8%至10.7%，男子为1.1%至13.8%），1990年至2006年观察到补充鱼油（女性为1.6%至18.1%，男性为3.3%至22.2%）。然而，维生素A、β-胡萝卜素、维生素C和维生素E补充剂的使用在1994年或1998年达到顶峰，然后稳步下降。在同一年龄组中，复合维生素、维生素D、叶酸和鱼油的使用长期增加。总之，随着时间的推移，许多类型的膳食补充剂的使用有所增加，但抗氧化剂补充剂的使用有所下降。同一年龄组补充剂使用率的长期增加表明，人口老龄化不是增加的主要原因。在卫生专业人员中的这些发现需要在普通人群中复制。
Most studies on the prevalence of supplement use in the United States were cross-sectional or evaluated trends in limited variety of supplements. The objective of this study was to describe the longitudinal and secular trend of dietary supplement use over the past 20 years in health professionals using data from two large prospective cohorts. We analyzed cohort data from 1986 to 2006 in the Nurses' Health Study (NHS) and the Health Professionals Follow-Up Study (HPFS). In 1986, 74,194 women aged 40 to 65 years in the NHS and 50,497 men aged 40 to 75 years in the HPFS were included. Use of dietary supplements including multivitamins, vitamins, and minerals was repeatedly asked every 4 years. Generalized estimating equation models were used for repeated analysis. Prevalence of use of any supplement increased among both women (71.3% to 88.3%) and men (56.4% to 80.7%) from 1986 to 2006. Notably, longitudinal increases in the prevalence of use of vitamin D (2.2% to 32.2% for women and 1.1% to 6.7% for men), folic acid (0.8% to 10.7% for women and 1.1% to 13.8% for men), and fish oil (1.6% to 18.1% for Women and 3.3% to 22.2% for men) supplements Were observed from 1990 to 2006. However, the use of vitamin A, beta carotene, vitamin C, and vitamin E supplements peaked in 1994 or 1998, then declined steadily. A secular increase in use of multivitamins, vitamin D, folic acid, and fish oil across same age group was noted. In conclusion, the use of many types of dietary supplements has increased over time, but the use of antioxidant supplements has declined. The secular increase in the prevalence of use of supplements across the same age group suggests that aging of the population is not the primary reason for the increase. These findings in health professionals need to be replicated in the general populations.