Psychopathological comorbidity in cocaine users in outpatient treatment
Psychopathological comorbidity in cocaine users in outpatient treatment
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DOI：
10.20882/adicciones.124
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发表时间：
2014-01-01
期刊：
影响因子：
3
通讯作者：
Rodriguez de Fonseca, Fernando
中科院分区：
文献类型：
--
作者：
Araos, Pedro;Vergara-Moragues, Esperanza;Rodriguez de Fonseca, Fernando
吸毒成瘾是一个日益严重的健康问题，其并发症突出表明，与滥用和依赖同时发生的精神障碍发病率很高。这种精神病理学的并发症根据消费时间和患者的年龄而变化。早期发现与毒品消费有关的精神病理障碍是优化医疗保健和改善预后的必要条件。本研究的主要目的是估计人群中寻求门诊治疗的可卡因使用的精神病理性共病的患病率和特点。我们招募了110名受试者使用可卡因鼻吹入评价与PRISM（精神病学研究访谈的物质和精神障碍），半结构化的诊断访谈，区分原发性精神障碍的药物引起的。该人群中男性占86.4%，平均年龄为36.5岁。他们表现出病理性使用可卡因的7年，精神病理学的存在与较高数量的DSM-IV-TR（精神疾病诊断和统计手册-IV-TR）物质依赖性标准。某些精神病理学合并症的终生患病率为61.8%，突出的是心境障碍（34.5%），其次是焦虑障碍（22.7%）和精神病性障碍（15.5%）。约20%的人表现为反社会人格障碍，21%的人表现为边缘型人格障碍。在情绪障碍和精神障碍中，诱发性障碍更常见，而原发性障碍在焦虑中更普遍。
Cocaine addiction is a growing health problem and among its complications highlights the high prevalence of mental disorders co-occurring with abuse and dependence. This psychopathological comorbidity varies according to the time of consumption and the age of the patient. Early detection of psychopathological disorders associated with drug consumption is necessary to optimize health care and to improve the prognosis. The main aim of the present study was to estimate the prevalence and characteristics of psychopathological comorbidity in a population of subjects seeking outpatient treatment for cocaine use. We recruited 110 subjects using cocaine by nasal insufflations evaluated with the PRISM (Psychiatric Research Interview for Substance and Mental Disorders), a semi-structured diagnostic interview that differentiates primary mental disorders from those induced by the drug. This population presented 86.4% male and had a mean age of 36.5. They displayed a pathological use of cocaine of 7 years and the presence of psychopathology was associated with a higher number of DSM-IV-TR (Diagnostic and Statistical Manual of Mental Disorders-IV-TR) criteria for substance dependence. The lifetime prevalence of some psychopathological comorbidity was 61.8%, highlighting mood disorders (34.5%), followed by anxiety disorders (22.7%) and psychotic disorders (15.5%). About 20% showed antisocial personality disorder and 21% borderline personality disorder. From among mood and psychotic disorders, the induced disorders were more frequent, while the primary disorders were more prevalent in anxiety.