NOMOGRAMS FOR CORRECTION OF BLOOD PO2, PCO2, PH AND BASE EXCESS FOR TIME AND TEMPERATURE
NOMOGRAMS FOR CORRECTION OF BLOOD PO2, PCO2, PH AND BASE EXCESS FOR TIME AND TEMPERATURE
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DOI：
10.1152/jappl.1966.21.5.1484
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发表时间：
1966-01-01
影响因子：
3.3
通讯作者：
NUNN, JF
中科院分区：
文献类型：
--
作者：
KELMAN, GR;NUNN, JF
血液PO2、PCO2、ph和碱过量测量中的误差主要来自两个来源，即采样和测量之间发生的代谢变化，以及实验对象和测量电极之间的温差。为了简化对这些错误的必要修正，已经构造了nomogram。这些包括：对经过时间的co2分压、PO2、pH值和碱过量的校正，基于假设血液从恒温对象中取出，并允许自发冷却到20-24℃的环境温度，以及基于假设注射器在采样和分析之间保持在37℃的类似校正；校正PCO2， PO2和pH的电极和主体之间的温差；pH-温度系数允许该系数依赖于pH和co2分压；以及表示正常血红蛋白氧解离曲线的折线图以及使其适用于不同温度和酸碱状态所需的修正。这个图表是必要的，因为温度对PO2的影响取决于饱和度百分比。
Errors in the measurement of blood PO2, PCO2, pH. and base excess arise from two main sources metabolic changes which occur between sampling and measurement, and temperature differences between the experimental subject and the measuring electrode. Nomograms have been constructed to simplify the necessary corrections for these errors. These are as follows: cor-rections to PCO2, PO2, pH, and base excess for elapsed time, based on the assumption that blood is withdrawn from a normothermic sub- ject, and allowed to cool spontaneously towards an ambient temperature of 20-24 C, and similar corrections based on the assumption that the syringe is maintained at 37 C between sampling and analysis; corrections to PCO2, PO2, and pH for temperature differences between the electrode and the subject; the pH-temperature coefficient allowing for the dependance of this coefficient on pH and PCO2; and line charts representing the normal oxyhemoglobin dissociation curve and the corrections necessary to make this applicable to various temperatures and acid-base states. This chart is necessary since the effect of temperature on PO2 depends upon the percentage saturation.