OCCLUSAL DYSFUNCTION AND STRESS - AN EXPERIMENTAL-STUDY IN MACAQUE MONKEYS
OCCLUSAL DYSFUNCTION AND STRESS - AN EXPERIMENTAL-STUDY IN MACAQUE MONKEYS
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DOI：
10.1111/j.1365-2842.1981.tb00469.x
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发表时间：
1981-01-01
影响因子：
2.9
通讯作者：
BUDTZJORGENSEN, E
中科院分区：
文献类型：
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作者：
BUDTZJORGENSEN, E
一个功能失调的咬合关系，在6只猕猴病毒猴插入咬合夹板，提高了3-4毫米的咬合垂直尺寸，并纳入干扰到咬合。通过竞争性蛋白结合分析测量血浆和24小时尿液样品的皮质醇水平。插入夹板后，平均24小时尿皮质醇排泄率立即升高约2倍，尿量和体重显著降低。血浆皮质醇水平无明显升高。在3周的实验期间，牙齿显示出增加的流动性和咬合磨损小平面上的夹板。在整个实验期间，尿皮质醇排泄率显著升高。尿皮质醇水平下降到基础值时，夹板被删除。该动物模型产生的实验证据支持咬合关系失调可能导致与情绪压力相关的磨牙症的假设。
A dysfunctional occlusal relationship was produced in six Macaca irus monkeys by insertion of occlusal splints which raised the vertical dimension of occlusion by 3–4 mm and incorporated interferences into the occlusion. Cortisol levels of plasma and 24 h urine samples were measured by competitive protein‐binding analysis. After insertion of the splints there was an immediate, approximately two‐fold rise of the mean 24 h urinary cortisol excretion rate and a significant decrease of urinary volume and body weight. The plasma cortisol level did not rise significantly. During the 3 weeks experimental period the teeth showed increasing mobility and occlusal wear facets developed on the splints. Urinary cortisol excretion rates were significantly elevated throughout the experimental period. Urinary cortisol levels declined to basal values when the splints were removed. This animal model produces experimental evidence in support of the hypothesis that a dysfunctional occlusal relationship may result in bruxism associated with emotional stress.