PRENATAL WEIGHT-GAIN PATTERNS AND SPONTANEOUS PRETERM BIRTH AMONG NONOBESE BLACK-AND-WHITE WOMEN
PRENATAL WEIGHT-GAIN PATTERNS AND SPONTANEOUS PRETERM BIRTH AMONG NONOBESE BLACK-AND-WHITE WOMEN
复制标题
DOI：
10.1016/0029-7844(95)00067-2
复制
发表时间：
1995-06-01
影响因子：
7.2
通讯作者：
GOLDENBERG, RL
中科院分区：
文献类型：
--
作者：
HICKEY, CA;CLIVER, SP;GOLDENBERG, RL
目的：研究产前体重增加和自发性早产之间的关系，使用医学研究所（IOM）guidelines.Methods：非肥胖低收入黑人（677例）和白色（338例）妇女被分组的种族和孕前体重指数（BMI）低（小于19.8）或正常（19.8-26.0）。总增益的关系（孕早期）和每周增重率在控制社会人口统计学和生殖变量以及最后一次体重观察和分娩之间的时间的同时，确定了（第二和第三孕期）至自发性早产的时间。对于所有女性来说，（+/-标准差）妊娠早期体重增加为2.48 +/- 3.36 kg，第二和第三孕期的平均增重率分别为0.49 ± 0.21和0.45 ± 0.28 kg/周。早期或中期妊娠体重增加较低与自发性早产的调整优势比（OR）增加无关。妊娠晚期增重率低于国际移徙组织建议范围的下限在所有妇女中，体重指数低于0.38 kg/周的低体重妇女，体重指数低于0.37 kg/周的正常体重妇女，（OR 2.46，95%置信区间[CI] 1.53-3.92），所有黑人女性（OR 1.98，95% CI 1.16-3.41），所有白色女性（OR 4.05，95% CI 1.41-11.66）。结论：这些观察结果表明，使用IOM指南定义的低妊娠晚期体重增加率，与非肥胖黑人和白色妇女自发性早产风险增加有关。
Objective: To examine the relationship between prenatal weight gain and spontaneous preterm delivery, using the Institute of Medicine (IOM) guidelines.Methods: Nonobese low-income black (677 subjects) and white (338) women were grouped by ethnicity and prepregnancy body mass index (BMI) as low (less than 19.8) or normal (19.8-26.0). The relationship of total gain (first trimester) and weekly rate of gain (second and third trimester) to spontaneous preterm delivery was determined while controlling for sociodemographic and reproductive variables as well as for time between last weight observation and delivery.Results: For all women combined, the mean (+/- standard deviation) weight gain during the first trimester was 2.48 +/- 3.36 kg, and the mean rate of gain during the second and third trimesters was 0.49 +/- 0.21 and 0.45 +/- 0.28 kg/week, respectively. Low first- or second-trimester weight gain was not associated with increased adjusted odds ratios (OR) for spontaneous preterm delivery. Third-trimester rates of gain below the lower limit of the IOM-recommended range (less than 0.38 kg/week with low BMI, less than 0.37 kg/week with normal BMI) were associated with increased preterm delivery among all women (OR 2.46, 95% confidence interval [CI] 1.53-3.92), all black women (OR 1.98, 95% CI 1.16-3.41), and all white women (OR 4.05, 95% CI 1.41-11.66).Conclusion: These observations suggest that a low third-trimester rate of weight gain, defined using IOM guidelines, is associated with an increased risk of spontaneous preterm delivery among nonobese black and white women.