Mercury in the Umbilical Cord: Implications for Risk Assessment for Minamata Disease.
Mercury in the Umbilical Cord: Implications for Risk Assessment for Minamata Disease.
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DOI：
10.1289/ehp.94102548
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发表时间：
1994-06
影响因子：
10.4
通讯作者：
Weihe P
中科院分区：
文献类型：
--
作者：
Dalgard C;Grandjean P;Jorgensen PJ;Weihe P
脐带组织是从法罗群岛的50个新生儿中获得的，那里的高汞摄入量是由于摄入了领航鲸肉。汞浓度显着相关的母亲鲸鱼肉晚餐在怀孕期间的频率和脐带血和母亲的头发中的汞浓度。研究结果与日本水俣市12名被诊断为先天性甲基汞中毒的婴儿脐带组织中汞的公布值进行了比较。从法罗群岛样本中获得的回归系数来看，水俣地区脐带汞浓度中位数为4.95 nmol/g干重，相当于668 nmol/l脐带血和114 nmol/g母体毛发。这些水平与胎儿对甲基汞暴露增加的易感性的其他证据一致。
Umbilical cord tissue was obtained from 50 births in the Faroe Islands, where high mercury intake is due to ingestion of pilot whale meat. The mercury concentration correlated significantly with the frequency of maternal whale meat dinners during pregnancy and with mercury concentrations in umbilical cord blood and in maternal hair. The results were compared with published values for mercury in umbilical cord tissue from 12 infants diagnosed with congenital methylmercury poisoning in Minamata, Japan. From the regression coefficients obtained in the Faroese samples, the median umbilical cord mercury concentration of 4.95 nmol/g dry weight in Minamata would correspond to 668 nmol/l cord blood and 114 nmol/g maternal hair. These levels agree well with other evidence of susceptibility of the fetus to increased exposure to methylmercury.