Relationship between endogenous hydrogen sulfide and blood stasis syndrome based on the Qi-blood theory of chinese medicine
Relationship between endogenous hydrogen sulfide and blood stasis syndrome based on the Qi-blood theory of chinese medicine
复制标题
基于中医气血理论探讨内源性硫化氢与血瘀证的关系
DOI：
10.1007/s11655-013-1567-7
复制
发表时间：
2013-09-01
影响因子：
2.9
通讯作者：
Wang Xue-mei
中科院分区：
文献类型：
--
作者：
Li Wei-wei;Guo Hao;Wang Xue-mei
“气”和“血”是中医的两个基本概念。由于气是无形的，所以中医和西医对于气的概念仍然存在争议。然而，内源性硫化氢（H2S）和其他气体信号分子为理解中药气的本质提供了新的途径。血瘀证是CM的常见证候。中医理论认为，血瘀证的发生与气的运行密切相关，气与血对生理功能的调节密不可分。近年来，越来越多的证据表明血瘀证与微循环障碍之间存在密切的相关性。本文基于中医气血理论探讨内源性H2S与血瘀证的关系。我们发现内源性H2S可能是中医气概念的物质基础，而微循环障碍是血瘀证的病理基础。由于气与血瘀证的发生、发展密切相关，内源性H2S可能通过改善微循环功能，在防治血瘀证方面发挥重要作用。
"Qi" and "blood" are two essential concepts in Chinese medicine (CM). As qi is intangible, the concept of qi is still controversial between CM and Western medicine. However, the endogenous hydrogen sulfide (H2S) and other gaseous signaling molecules provides a new approach for understanding the essence of qi in CM. Blood stasis syndrome is a common syndrome in CM. According to the CM theory, the incidence of blood stasis syndrome is closely correlated to the reckless movement of qi, as qi and blood are inseparable in regulating physiological functions. In recent years, more and more evidences suggest a close correlation between blood stasis syndrome and microcirculation dysfunction. In this paper, we discuss the relationship between endogenous H2S and blood stasis syndrome based on qi-blood theory of CM. We found that endogenous H2S maybe a material basis in concept of qi in CM, while dysfunctional microcirculation is the pathological basis of the blood stasis syndrome. As qi is closely associated with incidence and progression of blood stasis syndrome, endogenous H2S may play an important role in preventing and treating the blood stasis syndrome by improving the function of microcirculation.