Formation of hypertrophic scars: Evolution and susceptibility
Formation of hypertrophic scars: Evolution and susceptibility
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DOI：
10.3109/2000656x.2012.669184
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发表时间：
2012-01-01
影响因子：
1.2
通讯作者：
Niessen, Frank B.
中科院分区：
文献类型：
--
作者：
Delavary, Babak Mahdavian;Van der Veer, Willem M.;Niessen, Frank B.
增生性瘢痕的形成是创面愈合的常见并发症，目前对其发生率和危险因素知之甚少。我们的目的是分析术后增生性瘢痕的发生率、进展和消退情况，并确定增生性瘢痕的危险因素。接受过双侧乳房缩小术或胸骨正中切开的患者被纳入研究范围。所有患者分别于术后3个月和12个月进行检查。我们在术后3个月和12个月记录：身高、体重、过敏状态、吸烟情况、皮肤类型、晒黑情况和疤痕形状。在纳入的204名患者中，122名(60%)在手术后12个月内形成了增生性瘢痕。在这些患者中，117例(96%)在手术后3个月内形成增生性瘢痕。术后12个月，66/204例(32%)有增生性瘢痕。在66例术后3个月的增生性瘢痕患者中，31例(47%)术后3个月和12个月S的增生性瘢痕消退。吸烟和年龄与增生性瘢痕的形成有关。总而言之，60%的患者术后出现增生性瘢痕，通常是在术后前三个月。大多数3个月后出现的增生性瘢痕在12个月后仍然肥大。年轻、不吸烟的患者更容易形成增生性瘢痕。
Formation of hypertrophic scars is a common complication of wound healing, and at present little is known about the incidence and risk factors. Our aim was to analyse the incidence, progression, and regression of postoperative hypertrophic scars over time and to identify risk factors of hypertrophic scars. Patients who had had bilateral reduction mammoplasty or median sternotomy incision were included in the study. All patients were examined at 3 and 12 months postoperatively. We recorded: height, weight, allergy status, smoking status, skin type, tanning, and shape of the scar 3 and 12 months postoperatively. Of the 204 patients who were included, 122 (60%) developed a hypertrophic scar within 12 months of operation. Of these patients, 117 (96%) developed a hypertrophic scar within 3 months of operation. Twelve months postoperatively, 66/204 patients (32%) had a hypertrophic scar. In 31 of the 66 of the patients with a hypertrophic scar 3 months postoperatively (47%), the hypertrophic scar(s) regressed after 3 and 12 months. Smoking and age were associated with formation of hypertrophic scars. In conclusion, 60% of patients developed hypertrophic scars postoperatively, typically during the first three months. Most hypertrophic scars that are present after three months are still hypertrophic after 12 months. Young, non-smoking patients are more susceptible to formation of hypertrophic scars.