Cost Effectiveness of a Cultural Physical Activity Intervention to Reduce Blood Pressure Among Native Hawaiians with Hypertension.

Cost Effectiveness of a Cultural Physical Activity Intervention to Reduce Blood Pressure Among Native Hawaiians with Hypertension.
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DOI:
10.1007/s41669-021-00291-6
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发表时间:
2022-01
期刊:
PharmacoEconomics - open
影响因子:
--
通讯作者:
Kaholokula JK
Kaholokula JK
中科院分区:
其他
文献类型:
--
作者:
Railey AF;Muller C;Noonan C;Schmitter-Edgecombe M;Sinclair K;Kim C;Look M;Kaholokula JK

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本研究的目的是计算成本,并评估通过社区组织提供的基于文化的身体活动干预是否具有成本效益,以降低夏威夷原住民高血压成年人的血压。夏威夷的六个社区组织在2015年至2019年期间完成了一项随机对照试验。总体而言,263名患有不受控制的高血压(收缩压≥ 140 mmHg,舒张压≥ 90 mmHg)的夏威夷原住民成年人被随机分配到为期12个月的草裙舞(传统夏威夷舞蹈)课程和自我调节课程的干预组,或仅接受教育的候补对照组。主要结果是与对照组相比,在基线和干预3,6和12个月时收集的收缩压变化。计算主要和次要结局的增量成本效果比(ICER)。非参数自举和敏感性分析评估了参数和结果的不确定性。平均干预成本为361美元/人,6个月ICER为收缩压降低103美元/mmHg,舒张压降低95美元/mmHg。在12个月时,干预组保持血压下降,超过了基于血压结果的常规护理的下降。12个月时的血压变化导致收缩压ICER降低100美元/mmHg,舒张压ICER降低93美元/mmHg。敏感性分析表明,在估计的干预成本,该计划将降低收缩压5毫米汞柱的概率分别为67%和2.5%,在6个月和12个月。为期6个月的奥拉侯计划可能是低资源社区组织的成本效益。干预组在6个月和12个月时维持血压降低有助于潜在的成本效益。未来的研究应进一步评估成本效益的土著体育活动计划在类似的设置和建模的生命周期成本和质量调整生命年。NCT 02620709。在线版本包含补充材料,可通过10.1007/s41669-021-00291-6获得。
The aim of this study was to calculate the costs and assess whether a culturally grounded physical activity intervention offered through community-based organizations is cost effective in reducing blood pressure among Native Hawaiian adults with hypertension. Six community-based organizations in Hawai‘i completed a randomized controlled trial between 2015 and 2019. Overall, 263 Native Hawaiian adults with uncontrolled hypertension (≥ 140 mmHg systolic, ≥ 90 mmHg diastolic) were randomized to either a 12-month intervention group of hula (traditional Hawaiian dance) lessons and self-regulation classes, or to an education-only waitlist control group. The primary outcome was change in systolic blood pressure collected at baseline and 3, 6, and 12 months for the intervention compared with the control group. Incremental cost-effectiveness ratios (ICERs) were calculated for primary and secondary outcomes. Non-parametric bootstrapping and sensitivity analyses evaluated uncertainty in parameters and outcomes. The mean intervention cost was US$361/person, and the 6-month ICER was US$103/mmHg reduction in systolic blood pressure and US$95/mmHg in diastolic blood pressure. At 12 months, the intervention group maintained reductions in blood pressure, which exceeded reductions for usual care based on blood pressure outcomes. The change in blood pressure at 12 months resulted in ICERs of US$100/mmHg reduction in systolic blood pressure and US$93/mmHg in diastolic blood pressure. Sensitivity analyses suggested that at the estimated intervention cost, the probability that the program would lower systolic blood pressure by 5 mmHg was 67 and 2.5% at 6 and 12 months, respectively. The 6-month Ola Hou program may be cost effective for low-resource community-based organizations. Maintenance of blood pressure reductions at 6 and 12 months in the intervention group contributed to potential cost effectiveness. Future studies should further evaluate the cost effectiveness of indigenous physical activity programs in similar settings and by modeling lifetime costs and quality-adjusted life-years. NCT02620709. The online version contains supplementary material available at 10.1007/s41669-021-00291-6.
文化舞蹈计划改善了夏威夷原住民和太平洋岛民的高血压管理:一项飞行员随机试验。
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