CRYPTOCOCCAL INFECTIONS IN PATIENTS WITH ACQUIRED-IMMUNE-DEFICIENCY-SYNDROME
CRYPTOCOCCAL INFECTIONS IN PATIENTS WITH ACQUIRED-IMMUNE-DEFICIENCY-SYNDROME
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DOI：
10.1016/0002-9343(86)90176-2
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发表时间：
1986-07-01
影响因子：
5.9
通讯作者：
KAPILA, R
中科院分区：
文献类型：
--
作者：
ENG, RHK;BISHBURG, E;KAPILA, R
Cyptococcus neoformans is a major pathogen in patients with acquired immune deficiency syndrome and was found to infect 13.3 percent of such patients seen at two medical centers. Serum cytococcal antigen levels were as high as 1:2,000,000 and, despite therapy, often remained elevated. Antigen titers in the cerebrospinal fluid generally declined at an expected rate in the survivors. The significance of high antigen titers in the blood after a prolonged course of therapy with amphotericin B and 5-flucytosine is unknown.
