Pediatric nephrolithiasis and the link to bone metabolism.
Pediatric nephrolithiasis and the link to bone metabolism.
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小儿肾结石及其与骨代谢的联系。
DOI：
10.1097/mop.0000000000000069
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发表时间：
2014
影响因子：
3.6
通讯作者：
Ayoob,RoseMary
中科院分区：
文献类型：
--
作者：
Schwaderer,AndrewLawrence;Kusumi,Kirsten;Ayoob,RoseMary
低骨密度导致的骨质疏松症和骨折风险是巨大的，对患者的生活质量和医疗费用具有潜在的深远影响。骨量是在儿童年龄范围内获得的，因此识别和治疗高危儿童是很重要的。儿科患者的回顾性研究表明，柠檬酸盐或噻嗪类利尿剂治疗可改善骨密度。我们现在了解到肾结石与低骨密度之间存在联系。为了改善我们当前患者的医疗保健，同时保护他们未来的健康，重要的是确定低BMD并启动策略来改善“高危”儿童的BMD。
The healthcare burden from low BMD with subsequent osteoporosis and fracture risk is immense with potential far-reaching effects in patient quality of life and healthcare expense. Bone mass is acquired in the pediatric age range, thus it is important to identify and treat at-risk children. Retrospective reviews in pediatric patients indicate that citrate or thiazide diuretic treatment may improve BMD. We now understand that a relationship exists between nephrolithiasis and low BMD. To improve healthcare for our current patients as well as protect their future health it is important to identify low BMD and initiate strategies to improve BMD in ‘at-risk’children.