MUSCULAR FATIGUE INVESTIGATED BY PHOSPHORUS NUCLEAR MAGNETIC-RESONANCE

MUSCULAR FATIGUE INVESTIGATED BY PHOSPHORUS NUCLEAR MAGNETIC-RESONANCE
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DOI：
10.1038/274861a0
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发表时间：
1978-01-01
期刊：
NATURE
影响因子：
64.8
通讯作者：
WILKIE, DR
WILKIE, DR
中科院分区：
综合性期刊1区
文献类型：
--
作者：
DAWSON, MJ;GADIAN, DG;WILKIE, DR

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使用 31P NMR（磷核磁共振）对青蛙肌肉的肌肉疲劳进行研究，以测量几种关键代谢物的水平和利用率以及 ATP 水解的自由能变化。力量的发展与代谢物水平密切相关，并且与 ATP 水解的速率成正比。
Muscular fatigue was studied in frog muscle using 31P NMR [phosphorus nuclear magnetic resonance] to measure the levels and rates of utilization of several key metabolites and the free-energy change for ATP hydrolysis. Force development is closely correlated with metabolite levels and is proportional to the rate at which ATP is hydrolyzed.