Ensembl 2002: accommodating comparative genomics
Ensembl 2002: accommodating comparative genomics
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DOI：
10.1093/nar/gkg083
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发表时间：
2003-01-01
影响因子：
14.9
通讯作者：
Birney, E
中科院分区：
文献类型：
--
作者：
Clamp, M;Andrews, D;Birney, E
Ensembl（http：//www.ensembl.org/）数据库项目提供了一个生物信息学框架，围绕大基因组序列组织生物学。这是一个全面的来源，稳定的自动注释人类，小鼠和其他基因组序列，可作为一个互动的网站或作为在文件。Ensembl还整合了来自外部来源的手动注释的基因结构。除了是基因组注释的主要来源之一，Ensembl还是一个开源软件工程项目，旨在开发能够处理非常大的基因组和相关要求的便携式系统。这些范围从序列分析到数据存储和可视化以及安装在世界各地的公司和学术场所。随着人类和小鼠基因组序列的可用性以及更多脊椎动物序列的后续发展，Ensembl最近的许多发展都集中在开发自动比较基因组分析和可视化上。
The Ensembl (http://www.ensembl.org/)database project provides a bioinformatics framework to organise biology around the sequences of large genomes. It is a comprehensive source of stable automatic annotation of human, mouse and other genome sequences, available as either an interactive web site or as at files. Ensembl also integrates manually annotated gene structures from external sources where available. As well as being one of the leading sources of genome annotation, Ensembl is an open source software engineering project to develop a portable system able to handle very large genomes and associated requirements. These range from sequence analysis to data storage and visualisation and installations exist around the world in both companies and at academic sites. With both human and mouse genome sequences available and more vertebrate sequences to follow, many of the recent developments in Ensembl have focusing on developing automatic comparative genome analysis and visualisation.