Dose-dependent effects of alcohol on appetite and food intake

Dose-dependent effects of alcohol on appetite and food intake
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DOI:
10.1016/j.physbeh.2003.12.017
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发表时间:
2004-03-01
影响因子:
2.9
通讯作者:
Hetherington, MM
Hetherington, MM
中科院分区:
医学3区
文献类型:
--
作者:
Caton, SJ;Ball, M;Hetherington, MM

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为了检查酒精对食欲和食物摄入的潜在剂量反应效应,12名男性参加了三次实验室。每一次,他们都得到了一个标准的早餐,然后午餐3它之后,晚餐,4小时后。午餐前30分钟,受试者接受330 ml无酒精贮藏啤酒(263 U无酒精条件),相同量的贮藏啤酒加1单位(1 UA:8 g乙醇,498.2 kJ)或4单位酒精(4 UA:32 g乙醇,1203.8 kJ)。视觉模拟量表(VAS)评分的食欲和情绪前,后预负荷和午餐,然后在一天中每小时记录。与1次UA(4928 +/- 1245 kJ)相比,4次UA(5786 +/- 991 kJ)后的午餐摄入量(不包括前负荷的能量)显著更高。与其他预负荷相比,参与者在4 UA后的午餐时消耗更多的高脂肪咸食物。与其他前负荷相比,饥饿在一天中的4个UA之后被评定为更高,但饱腹感评级未能反映任何条件差异。在所有条件下,晚餐时的能量摄入量相似,一天中的总能量摄入量在4个UA(14,615 +/- 1540 kJ)后显著高于1个UA(13,204 +/- 2156 kJ)。总而言之,超过一定的阈值,酒精似乎会刺激食欲,部分原因是主观饥饿感水平升高。当这种情况发生时,能量摄入量不会在随后的膳食中减少。因此,酒精可以通过其对总能量摄入的加和效应和短期食欲刺激来促进正能量平衡。(C)2004爱思唯尔公司All rights reserved.
To examine the potential dose-response effect of alcohol on appetite and food intake, 12 males attended the laboratory on three occasions. On each occasion, they were given a standard breakfast, then lunch 3 It later, and dinner, 4 h after that. Thirty minutes before lunch, Ss received 330 ml of no-alcohol lager (263 U no-alcohol condition), the same amount of lager spiked with 1 unit (1 UA: 8 g ethyl alcohol, 498.2 kJ) or 4 units of alcohol (4 UA: 32 g ethyl alcohol, 1203.8 kJ). Visual analogue scale (VAS) ratings of appetite and mood were recorded before and after preloads and lunch, then hourly across the day. Intake at lunch (excluding energy from the preload) was significantly higher following 4 UA (5786 +/- 991 kJ) compared to 1 UA (4928 +/- 1245 kJ). Participants consumed more high-fat salty food items at lunch following 4 UA compared to the other preloads. Hunger was rated higher following 4 UA across the day in comparison to the other preloads, but fullness ratings failed to reflect any difference by condition. Energy intake at dinner was similar in all conditions and total energy intake across the day was significantly higher after 4 UA (14,615 +/- 1540 kJ) than after 1 UA (13,204 +/- 2156 kJ). In conclusion, above a certain threshold, alcohol appears to stimulate appetite in part, due to elevated levels of subjective hunger. When this occurs, energy intake is not reduced at subsequent meals. Thus, alcohol may contribute to positive energy balance via its additive effects to total energy intake and by short-term appetite stimulation. (C) 2004 Elsevier Inc. All rights reserved.