Long-term effects of adolescent stress on neophobic behaviors in zebra finches are modulated by social context when in adulthood.
Long-term effects of adolescent stress on neophobic behaviors in zebra finches are modulated by social context when in adulthood.
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DOI：
10.1016/j.yhbeh.2017.02.004
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发表时间：
2017-04
影响因子：
3.5
通讯作者：
Spencer KA
中科院分区：
文献类型：
--
作者：
Emmerson MG;Spencer KA
在青春期经历压力会增加成年后的新恐惧行为，但大多数测试都是在没有同种的情况下进行的。同种可以调节对压力源的反应，例如通过充当“社会缓冲器”来减弱对压力源的厌恶评价。在这里，我们调查的长期影响，青少年压力的行为反应，新的刺激（一个温和的压力源）在社会环境中的附属雀形目鸟类，斑胸草雀。在青春期早期（第40-60天）或晚期（第65-85天），给鸟（n = 66）注射生理盐水或皮质酮（CORT）。给予CORT以模拟生理应激反应，并给予生理盐水作为对照。在成年期，鸟类对新环境的行为反应在同种存在和不存在的情况下都被记录下来。急性CORT反应也在青春期和成年期进行了量化。我们的研究结果表明，社会背景调解青少年压力的任何长期影响的明确证据。在存在熟悉同种的情况下，未检测到治疗效应。个别而言，在青春期早期给予CORT的鸟类进入新环境的速度较慢，在同一新环境中栖息的时间更长，如果是雌性，则进行更多的风险评估。在青春期后期给药的鸟未受影响。未检测到对CORT的治疗效应，但青少年的CORT浓度高于成人。我们的研究结果首次表明，成年期熟悉的同类可以缓冲青春期早期发生的压力的长期影响。青春期皮质酮升高会增加成年期的恐新行为。成年期常见的同种物缓冲了青少年压力的长期影响。皮质酮可能是行为持续变化背后的一种内分泌机制。
Experiencing stress during adolescence can increase neophobic behaviors in adulthood, but most tests have been conducted in the absence of conspecifics. Conspecifics can modulate responses to stressors, for example by acting as ‘social buffers’ to attenuate the aversive appraisal of stressors. Here, we investigate the long-term effects of adolescent stress on the behavioral responses to novel stimuli (a mild stressor) across social contexts in an affiliative passerine bird, the zebra finch. During early (days 40–60) or late (days 65–85) adolescence the birds (n = 66) were dosed with either saline or the hormone corticosterone (CORT). CORT was given in order to mimic a physiological stress response and saline was given as a control. In adulthood, the birds' behavioral responses to a novel environment were recorded in both the presence and absence of conspecifics. An acute CORT response was also quantified in adolescence and adulthood. Our findings show clear evidence of social context mediating any long-term effects of adolescent stress. In the presence of familiar conspecifics no treatment effects were detected. Individually, birds dosed with CORT in early adolescence were slower to enter a novel environment, spent more time perching in the same novel environment, and, if female, engaged in more risk assessment. Birds dosed in late adolescence were unaffected. No treatment effects were detected on CORT, but adolescents had a higher CORT concentration than adults. Our results are the first to suggest that familiar conspecifics in adulthood can buffer the long-term effects of stress that occurred during early adolescence. Elevated corticosterone in adolescence increases neophobic behaviors in adulthood. Familiar conspecifics in adulthood buffer long-term effects of adolescent stress. Corticosterone may be an endocrine mechanism behind sustained changes in behavior.