Tissue reaction to alumina implants inserted into the tibiae of rats.
Tissue reaction to alumina implants inserted into the tibiae of rats.
复制标题
对插入大鼠胫骨的氧化铝植入物的组织反应。
DOI：
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发表时间：
1993
期刊：
影响因子：
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通讯作者：
T. Suetsugu
中科院分区：
文献类型：
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作者：
F. Takeshita;K. Morimoto;T. Suetsugu
我们检查了三种氧化铝植入物的组织反应-单晶氧化铝（SA），致密多晶氧化铝（DPA）和多孔多晶氧化铝（PPA）-经皮质插入，延伸到大鼠胫骨髓管，并使用图像处理系统评估骨反应的定量差异。三种氧化铝周围新形成骨的成熟程度无差异。SA和DPA被连续的骨层包裹，但PPA周围局部有骨组织附着。对照部位骨小梁的大小和数量按时间顺序减少。DPA和PPA表面可见多核巨细胞，SA表面未见。定量评价表显示，在骨接触率、骨接触厚度和骨接触面积方面，SA最高，DPA次之，PPA最低。这些数据表明，SA作为植入材料上级其他两种。
We examined the tissue reaction to three alumina implants--single-crystal alumina (SA), dense polycrystal alumina (DPA), and porous polycrystal alumina (PPA)--inserted transcortically, extending into the medullary canal of rat tibiae, and assessed the quantitative differences in bone reaction using an image processing system. There was no difference in the degree of maturation of newly formed bone around the three kinds of alumina. SA and DPA were encapsulated with a continuous bone layer, but some bone tissue was attached focally around PPA. Bone trabeculae in the control site diminished in size and number chronologically. Multinucleated giant cells were observed on the surface of DPA and PPA, but not on SA. Tabulation of the quantitative evaluation indicated that SA showed the highest, DPA a lower, and PPA the lowest in bone contact rate, bone contact thickness, and bone contact area. These data suggest that SA is superior to the other two as an implant material.