Characteristics of Suicide Attempts in Anorexia and Bulimia Nervosa: A Case-Control Study
Characteristics of Suicide Attempts in Anorexia and Bulimia Nervosa: A Case-Control Study
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DOI：
10.1371/journal.pone.0023578
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发表时间：
2011-08-12
期刊：
影响因子：
3.7
通讯作者：
Schmidt, Ulrike
中科院分区：
文献类型：
--
作者：
Guillaume, Sebastien;Jaussent, Isabelle;Schmidt, Ulrike
目的：与其他饮食失调相比，神经性厌食症（AN）的自杀率最高，而自杀未遂率与神经性贪食症（BN）相似或更低。自杀未遂是自杀的关键预测因素，因此这种不匹配是有趣的。我们试图探讨是否有自杀行为的临床特征与AN，BN或没有进食障碍（艾德）之间的差异。方法：在一个队列的自杀行为（n = 1563）病例对照研究。44例AN患者和71例BN患者与235名非ED患者进行了比较，这些患者在性别、年龄和教育程度方面相匹配，使用自杀意图和严重程度的访谈措施。AN患者更有可能认真尝试（OR = 3.4，95%CI 1.4-7.9），死亡预期较高（OR = 3.7，95%CI 1.1-13.5），严重程度风险增加（OR = 3.4，95%CI 1.2-9.6）。BN患者与对照组无差异。艾德严重程度的临床指标与自杀未遂的严重程度相关。这可以解释AN中较高的自杀率。AN中较高的自杀完成率可能部分解释为AN患者更高的死亡欲望和他们更严重和致命的企图。
Objective: Compared to other eating disorders, anorexia nervosa (AN) has the highest rates of completed suicide whereas suicide attempt rates are similar or lower than in bulimia nervosa (BN). Attempted suicide is a key predictor of suicide, thus this mismatch is intriguing. We sought to explore whether the clinical characteristics of suicidal acts differ between suicide attempters with AN, BN or without an eating disorders (ED).Method: Case-control study in a cohort of suicide attempters (n = 1563). Forty-four patients with AN and 71 with BN were compared with 235 non-ED attempters matched for sex, age and education, using interview measures of suicidal intent and severity.Results: AN patients were more likely to have made a serious attempt (OR = 3.4, 95% CI 1.4-7.9), with a higher expectation of dying (OR = 3.7, 95% CI 1.1-13.5), and an increased risk of severity (OR = 3.4, 95% CI 1.2-9.6). BN patients did not differ from the control group. Clinical markers of the severity of ED were associated with the seriousness of the attempt.Conclusion: There are distinct features of suicide attempts in AN. This may explain the higher suicide rates in AN. Higher completed suicide rates in AN may be partially explained by AN patients' higher desire to die and their more severe and lethal attempts.