Involvement of thalamic paraventricular nucleus in the anticipatory reaction under food restriction in the rat.
Involvement of thalamic paraventricular nucleus in the anticipatory reaction under food restriction in the rat.
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DOI：
10.1292/jvms.66.1297
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发表时间：
2004-10
期刊：
影响因子：
--
通讯作者：
K. Nakahara;K. Fukui;N. Murakami
中科院分区：
文献类型：
--
作者：
K. Nakahara;K. Fukui;N. Murakami
为了研究哪些脑区参与大鼠限制喂养2小时的预期活动，我们研究了喂养前后c-Fos的表达。只有丘脑室旁核（tPVN）的c-Fos表达在进食前比进食后强。在建立了预期的自发活动节律后，损毁tPVN会减弱这种节律，但不会减弱明暗夹带节律。在长期tPVN损伤的大鼠中，未建立血液皮质酮水平的预期增加。这些结果表明，tPVN参与表达的预期反应下的食物限制方案。
To investigate which brain regions are involved in the anticipatory activity in rats restricted feeding for 2 hr, we examined c-Fos expression before and after feeding. Only the thalamic paraventricular nucleus (tPVN) showed c-Fos expression before feeding than after feeding. After the anticipatory locomotor activity rhythm was established, lesioning the tPVN attenuated this rhythm, but not the light-dark entrained rhythm. The anticipatory increase of blood corticosterone levels was not established in long-term tPVN-lesioned rats. These results suggest that the tPVN is involved in the expression of anticipatory reactions under a food-restricted regimen.