Dynamic three-dimensional MR renography for the measurement of single kidney function: Initial experience

Dynamic three-dimensional MR renography for the measurement of single kidney function: Initial experience
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DOI:
10.1148/radiol.2271020383
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发表时间:
2003-04-01
期刊:
影响因子:
19.7
通讯作者:
Kramer, EL
Kramer, EL
中科院分区:
医学1区
文献类型:
--
作者:
Lee, VS;Rusinek, H;Kramer, EL

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基于静脉注射低剂量(2 mL或0.01 mmol/kg)钆喷酸葡胺后2-3分钟内的肾脏信号强度测量,开发了一种测量单肾肾小球滤过率(GFR)和分裂肾功能的三维磁共振(MR)肾成像方法。在9名受试者中,单肾MR GFR指数与锝(Tc-99 m)二乙烯三胺五乙酸(DTPA)清除率相关性良好(r = 0.7-0.8),GFR值为7-48 mL/min。MR右肾分裂肾功能值(范围,32%-59%)也与Tc-99 m-DTPA放射性核素测量值相关良好(r = 0.76);两种方法之间的差异平均为0.8% +/- 8。磁共振肾成像与对比剂增强的肾脏和肾动脉磁共振成像一起进行沿着,总检查时间增加8分钟或更少。(C)RSNA,2003年。
A three-dimensional magnetic resonance (MR) renographic method to measure single kidney glomerular filtration rate (GFR) and split renal function was developed that is based on renal signal intensity measurements during 2-3 minutes after intravenous injection of a low dose (2 mL or 0.01 mmol/kg) of gadopentetate dimeglumine. In nine subjects, single kidney MR GFR indices correlated well with technetium (Tc-99m) diethylenetriaminepentaacetic acid (DTPA) clearance (r = 0.7-0.8) for GFR values of 7-48 mL/min. MR right kidney split renal function values (range, 32%-59%) also correlated well with Tc-99m-DTPA radionuclide measurements (r = 0.76); differences between the two methods averaged 0.8% +/- 8. MR renography was performed along with contrast material-enhanced MR imaging of the kidneys and renal arteries and added 8 minutes or less to the total examination time. (C) RSNA, 2003.