Use of the Novel Therapeutic Agent Miltefosine for the Treatment of Primary Amebic Meningoencephalitis: Report of 1 Fatal and 1 Surviving Case
Use of the Novel Therapeutic Agent Miltefosine for the Treatment of Primary Amebic Meningoencephalitis: Report of 1 Fatal and 1 Surviving Case
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DOI：
10.1093/cid/civ1021
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发表时间：
2016-03-15
影响因子：
11.8
通讯作者：
Visvesvara, Govinda S.
中科院分区：
文献类型：
--
作者：
Cope, Jennifer R.;Conrad, Dennis A.;Visvesvara, Govinda S.
原发性阿米巴脑膜脑炎（PAM）是一种由嗜热自由生活的福氏耐格里阿米巴引起的暴发性中枢神经系统感染。很少有存活的记录，缺乏适当的治疗。我们报告2例PAM，1例死亡，1例存活，用新型抗寄生虫药米替福新治疗。
Primary amebic meningoencephalitis (PAM) is a fulminant central nervous system infection caused by the thermophilic free-living ameba Naegleria fowleri. Few survivals have been documented and adequate treatment is lacking. We report 2 PAM cases, 1 fatal and 1 surviving, treated with the novel antiparasitic agent miltefosine.