Function and regulation of SRBC-induced contrasuppressor T cells which modulate suppression of MOPC-315 cell secretory differentiation in vivo and in vitro.
Function and regulation of SRBC-induced contrasuppressor T cells which modulate suppression of MOPC-315 cell secretory differentiation in vivo and in vitro.
复制标题
SRBC 诱导的反抑制 T 细胞的功能和调节，调节体内和体外 MOPC-315 细胞分泌分化的抑制。
DOI：
10.1007/bf02918153
复制
发表时间：
1988
影响因子：
4.4
通讯作者：
Kemp,JD
中科院分区：
文献类型：
--
作者：
Rohrer,JW;Kemp,JD
Contrasuppression was first described as a regulatory activity which counteracted suppressive influences on helper T cells and so promoted antibody responses [I-4]. A similar activity was seen which affected cellmediated immune responsiveness [5, 6]. Subsequently, Braley-Mullen [7-9] showed that such antisuppressive activity could be directly focused on B lymphocytes. In all of these situations, the effector cells of contrasuppression shared certain surface phenotypic markers. They all were IJ*, Vicia villosa lectin-adherent, Lyt 1", 2-T cells. Some investigators, including ourselves, have found that not all of these markers are found on all T cells which express this regulatory activity [10-12]. Indeed, the only constant marker of all contrasuppressor T cells so far described has been their adherence to F. villosa lectin-coated Petri plates.
