Investigation of scintillator coated CCDs for medical imaging

Investigation of scintillator coated CCDs for medical imaging
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用于医学成像的闪烁体涂层 CCD 的研究

DOI:
10.1109/tns.2005.862962
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发表时间:
2004
影响因子:
1.8
通讯作者:
Alan C. Perkins
Alan C. Perkins
中科院分区:
工程技术3区
文献类型:
--
作者:
J. Lees;D. Bassford;George W. Fraser;David Monk;Michael Early;Robert J. Ott;Ian Moody;Elaine Blackshaw;Alan C. Perkins

文献摘要

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我们描述了一种基于闪烁体涂层电荷耦合器件(CCD)的相机的发展,用于成像组织中小体积的放射性核素摄取。高分辨率伽马成像仪(HRGI)是一种准直、闪烁体涂层、低成本、使用低噪声ccd的成像仪。HRGI在光子计数模式下工作,使用peltier冷却器实现-5/spl度/C的工作温度。我们使用来自/sup 241/Am源的59.5 keV辐射和来自/sup 99 m/Tc源的140 keV伽马射线,测量了e2v Technologies Ltd的原型CCD的空间分辨率和效率,该CCD涂有500-/spl mu/m厚的Gadox (Gd/sub 2/O/sub 2/S(Tb))层。我们还使用/sup 99 m/Tc的幻影来描述我们的第一张图像。
We describe the development of a scintillator-coated charge coupled device (CCD) based camera for imaging small volumes of radionuclide uptake in tissues. The high-resolution gamma imager (HRGI) is a collimated, scintillator-coated, low cost, imager using low noise CCDs. The HRGI operates in photon counting mode using a peltier cooler to achieve an operating temperature of -5/spl deg/C. We have measured the spatial resolution and efficiency of a prototype CCD from e2v Technologies Ltd coated with a 500-/spl mu/m-thick Gadox (Gd/sub 2/O/sub 2/S(Tb)) layer using 59.5 keV radiation from a /sup 241/Am source and 140 keV gamma-rays from a /sup 99 m/Tc source. We also describe our first images using /sup 99 m/Tc phantoms.