Delirium in elderly adults: diagnosis, prevention and treatment.

Delirium in elderly adults: diagnosis, prevention and treatment.
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DOI:
10.1038/nrneurol.2009.24
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发表时间:
2009-04
影响因子:
38.1
通讯作者:
Inouye, Sharon K.
Inouye, Sharon K.
中科院分区:
医学1区
文献类型:
--
作者:
Fong, Tamara G.;Tulebaev, Samir R.;Inouye, Sharon K.

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谵妄是一种常见且严重的急性神经精神综合征,其核心特征是注意力不集中和整体认知功能障碍。谵妄的病因多种多样且是多因素的,通常反映了急性内科疾病、内科并发症或药物中毒的病理生理后果。谵妄的表现多种多样,因此经常被漏诊或漏诊。目前,谵妄的诊断基于临床,取决于某些特征的存在或不存在。谵妄的管理策略侧重于预防和症状管理。本文回顾了当前老年人谵妄的临床实践,包括该综合征的诊断、治疗、结果和经济影响。还讨论了未来的研究领域。
Delirium is a common and serious acute neuropsychiatric syndrome with core features of inattention and global cognitive dysfunction. The etiologies of delirium are diverse and multifactorial and often reflect the pathophysiological consequences of an acute medical illness, medical complication or drug intoxication. Delirium can have a widely variable presentation, and is often missed and underdiagnosed as a result. At present, the diagnosis of delirium is clinically based and depends on the presence or absence of certain features. Management strategies for delirium are focused on prevention and symptom management. This article reviews current clinical practice in delirium in elderly individuals, including the diagnosis, treatment, outcomes and economic impact of this syndrome. Areas of future research are also discussed.
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