VIRUS-SPECIFIC DOUBLE-STRANDED RNA IN POLIOVIRUS-INFECTED CELLS
VIRUS-SPECIFIC DOUBLE-STRANDED RNA IN POLIOVIRUS-INFECTED CELLS
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DOI：
10.1126/science.143.3610.1034
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发表时间：
1964-01-01
期刊：
影响因子：
56.9
通讯作者：
BECKER, Y
中科院分区：
文献类型：
--
作者：
BALTIMORE, D;DARNELL, JE;BECKER, Y
Poo病毒感染的HeLa细胞含有少量的RNA，其沉积速度略快于16S。这种RNA的密度低于病毒RNA，并能抵抗核糖核酸酶的消化。因此，它被认为是脊髓灰质炎病毒RNA的双链形式。发现大量该物质与膜状病毒特异性颗粒相关。
PoUovirus-infected HeLa cells contain a small amount of an RNA that sediments slightly faster than 16S. This RNA is less dense than viral RNA and resists digestion by ribonuclease. It is therefore, considered to be a double-stranded form of poliovirus RNA. A significant amount of this material is found in association with a membranous virus-specific particulate.