Transductional mapping of gene trmA responsible for the production of 5-methyluridine in transfer ribonucleic acid of Escherichia coli
Transductional mapping of gene trmA responsible for the production of 5-methyluridine in transfer ribonucleic acid of Escherichia coli
复制标题
大肠杆菌转移核糖核酸中负责产生 5-甲基尿苷的基因 trmA 的转导图谱
DOI：
10.1128/jb.124.1.92-98.1975
复制
发表时间：
1975
影响因子：
3.2
通讯作者：
Glenn R. Bjurk
中科院分区：
文献类型：
--
作者：
Glenn R. Bjurk
基因 trmA 负责在转移核糖核酸中产生 5-甲基尿苷（核糖胸苷），已位于大肠杆菌 K-12 染色体图上的 79 分钟处。在五因子杂交中，基因顺序显示为argH-trmA-rif-thiA-metA。 argH 和 trmA 之间的共转导频率为 65%。此外，trmA5突变被证明是隐性的，这与trmA基因是转移核酸（5-甲基尿苷）甲基转移酶的结构基因的观点一致。
The gene trmA, responsible for the production of 5-methyluridine (ribothymidine) in transfer ribonucleic acid, has been located at 79 min on the chromosomal map of Escherichia coli K-12. In five-factor crosses the gene order was shown to be argH-trmA-rif-thiA-metA. The co-transduction frequency between argH and trmA was 65%. Furthermore, the trmA5 mutation was shown to be recessive, in agreement with the notion that the trmA gene is the structural gene for the transfer tibonucleic acid (5-methyluridine) methyltransferase.