Mechanical Properties of Cervical Spinal Cord in Neonatal Piglet: In Vitro.
Mechanical Properties of Cervical Spinal Cord in Neonatal Piglet: In Vitro.
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DOI：
10.31487/j.nnb.2020.02.08
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发表时间：
2020
期刊：
影响因子：
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通讯作者：
Balasubramanian S
中科院分区：
文献类型：
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作者：
Singh A;Magee R;Balasubramanian S
新生儿脊髓组织对拉伸负荷的反应还没有得到很好的研究。在这项研究中，从12只2-4日龄仔猪中获得的分离的新鲜新生儿颈脊髓样品以500 mm/min的速率在单轴拉伸中进行测试，直到失败。报告的最大载荷、最大应力、最大应力下的应变百分比和弹性模量分别为14.6±3.4 N、0.34±0.11 MPa、29.3±5.4%和1.52±0.8 MPa。这些数据可以帮助了解新生儿脊髓的生物力学行为，并可以进一步用于计算建模，以更好地了解损伤机制，并帮助制定损伤预防策略。
The response of neonatal spinal cord tissue to tensile loading is not well-studied. In this study, isolated fresh neonatal cervical spinal cord samples, obtained from twelve 2-4 days old piglets, were tested in uniaxial tension at a rate of 500 mm/min until failure. Maximum load, maximum stress, percentage strain at maximum stress and modulus of elasticity were reported to be 14.6±3.4 N, 0.34±0.11 MPa, 29.3±5.4% and 1.52±0.8 MPa, respectively. These data can help understand the biomechanical behavior of the spinal cord in neonates and can be further used in computational modeling to understand injury mechanisms better and help develop injury prevention strategies.